Physical function and mental health trajectories in COVID-19 patients following invasive mechanical ventilation: a prospective observational study.

ABSTRACT: This prospective observational cohort study was performed to investigate the physical function and mental health trajectories of novel coronavirus disease 2019 (COVID-19) patients requiring invasive mechanical ventilation (IMV) after discharge from the intensive care unit (ICU). The study population consisted of 64 patients (median age, 60 years; 85.9% male; median IMV duration, 9 days). At ICU discharge, 28.1% of the patients had Medical Research Council (MRC) sum score < 48 points, and prolonged IMV was significantly associated with lower MRC sum score and handgrip strength. Symptoms were similar between groups at ICU discharge, and the symptoms most commonly reported as moderate-to-severe were impaired well-being (52%), anxiety (43%), tiredness (41%), and depression (35%). Although musc

SUBMITTER: Yamamoto H 

PROVIDER: S-EPMC10477337 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature