Independent association between age- and sex-specific metabolic syndrome severity score and cardiovascular disease and mortality.

ABSTRACT: Traditional metabolic syndrome (MetS) criteria have several limitations, which hinder its use in clinical practice. To overcome the limitations, we investigated the association between age- and sex-specific continuous MetS severity score (cMetS-S) and cardiovascular disease (CVD) and mortality beyond MetS components in the framework of the Tehran Lipid and Glucose Study. Participants aged 20-60 years at baseline were included in the study. We excluded participants with CVD, cancer, use of corticosteroids, estimated glomerular filtration rate < 30 ml/min/1.73 m², and those who were pregnant. We evaluated the association between cMetS-S with CVD and mortality over 18 years of follow-up among 8500 participants with continuous and quantile approaches using the Cox proportional hazar

SUBMITTER: Honarvar M 

PROVIDER: S-EPMC10480156 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature