Automatically tracking brain metastases after stereotactic radiosurgery.

ABSTRACT:

Background and purpose

Patients with brain metastases (BMs) are surviving longer and returning for multiple courses of stereotactic radiosurgery. BMs are monitored after radiation with follow-up magnetic resonance (MR) imaging every 2-3 months. This study investigated whether it is possible to automatically track BMs on longitudinal imaging and quantify the tumor response after radiotherapy.

Methods

The METRO process (MEtastasis Tracking with Repeated Observations was developed to automatically process patient data and track BMs. A longitudinal intrapatient registration method for T1 MR post-Gd was conceived and validated on 20 patients. Detections and volumetric measurements of BMs were obtained from a deep learning model. BM tracking was validated on 32 separate patients b

SUBMITTER: Hsu DG 

PROVIDER: S-EPMC10500025 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature