Ontology highlight
ABSTRACT:
SUBMITTER: Grana-Miraglia L
PROVIDER: S-EPMC10506723 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Graña-Miraglia Lucía L Morales-Lizcano Nadia N Wang Pauline W PW Hwang David M DM Yau Yvonne C W YCW Waters Valerie J VJ Guttman David S DS
PLoS computational biology 20230906 9
Chronic Pseudomonas aeruginosa (Pa) lung infections are the leading cause of mortality among cystic fibrosis (CF) patients; therefore, the eradication of new-onset Pa lung infections is an important therapeutic goal that can have long-term health benefits. The use of early antibiotic eradication therapy (AET) has been shown to clear the majority of new-onset Pa infections, and it is hoped that identifying the underlying basis for AET failure will further improve treatment outcomes. Here we gener ...[more]