Is Height^2.7 Appropriate for Indexation of Left Ventricular Mass in Healthy Adolescents? The Importance of Sex Differences.

ABSTRACT:

Background

Left ventricular mass (LVM) is an important predictor of cardiovascular risk. In adolescence, LVM is commonly indexed to height^2.7, although some evidence suggests that this may not fully account for sex differences.

Methods

We investigated appropriate allometric scaling of LVM to height, total lean mass, and body surface area, in a UK birth cohort of 2039 healthy adolescents (17±1 years). Allometric relationships were determined by linear regression stratified by sex, following log transformation of x and y variables [log(y)=a+b×log(x)], b is the allometric exponent.

Results

Log (LVM) showed linear relationships with log(height) and log(lean mass). Biased estimates of slope resulted when the sexes were pooled. The exponents were lower than the c

SUBMITTER: Taylor HCM 

PROVIDER: S-EPMC10510825 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature