Biosynthesis of Fusapyrone Depends on the H3K9 Methyltransferase, FmKmt1, in <i>Fusarium mangiferae</i>.

ABSTRACT: The phytopathogenic fungus Fusarium mangiferae belongs to the Fusarium fujikuroi species complex (FFSC). Members of this group cause a wide spectrum of devastating diseases on diverse agricultural crops. F. mangiferae is the causal agent of the mango malformation disease (MMD) and as such detrimental for agriculture in the southern hemisphere. During plant infection, the fungus produces a plethora of bioactive secondary metabolites (SMs), which most often lead to severe adverse defects on plants health. Changes in chromatin structure achieved by posttranslational modifications (PTM) of histones play a key role in regulation of fungal SM biosynthesis. Posttranslational tri-methylation of histone 3 lysine 9 (H3K9me3) is considered a hallmark of heterochromatin and establ

SUBMITTER: Atanasoff-Kardjalieff AK 

PROVIDER: S-EPMC10512364 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature