Phage Therapy in the Management of Urinary Tract Infections: A Comprehensive Systematic Review.

ABSTRACT: Urinary tract infections (UTIs) are a problem worldwide, affecting almost half a billion people each year. Increasing antibiotic resistance and limited therapeutic options have led to the exploration of alternative therapies for UTIs, including bacteriophage (phage) therapy. This systematic review aims at evaluating the efficacy of phage therapy in treating UTIs. We employed a comprehensive search strategy for any language, any animal, and any publication date. A total of 55 in vivo and clinical studies were included. Of the studies, 22% were published in a non-English language, 32.7% were before the year 1996, and the rest were after 2005. The results of this review suggest that phage therapy for UTIs can be effective; more than 72% of the included articles reported microbiological

SUBMITTER: Al-Anany AM 

PROVIDER: S-EPMC10523411 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature