An enigma of hypothyroidism and hyponatremia coexistence: a nationwide population-based retrospective study.

ABSTRACT:

Introduction

Hypothyroidism is a rare and possible cause of hyponatremia. However, the clinical epidemiology and risk of mortality (ROM) when they coexist still remain elusive.

Objectives

We assessed the epidemiology and ROM among index patients with coexisting hypothyroidism and hyponatremia via a national population database.

Patients and methods

This retrospective cohort study utilized Taiwan's National Health Insurance program database. Distributions of definite sociodemographic factors were analyzed. The annual incidence among the overall group and sex-subgroups was investigated. In addition, potential factors influencing the ROM were also evaluated.

Results

Of 4,549,226 patients from 1998 to 2015, a total of 3,140 index patients with concurrent hypothyroi

SUBMITTER: Chu CH 

PROVIDER: S-EPMC10541708 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature