PaxDb 5.0: Curated Protein Quantification Data Suggests Adaptive Proteome Changes in Yeasts.

ABSTRACT: The "Protein Abundances Across Organisms" database (PaxDb) is an integrative metaresource dedicated to protein abundance levels, in tissue-specific or whole-organism proteomes. PaxDb focuses on computing best-estimate abundances for proteins in normal/healthy contexts and expresses abundance values for each protein in "parts per million" in relation to all other protein molecules in the cell. The uniform data reprocessing, quality scoring, and integrated orthology relations have made PaxDb one of the preferred tools for comparisons between individual datasets, tissues, or organisms. In describing the latest version 5.0 of PaxDb, we particularly emphasize the data integration from various types of raw data and how we expanded the number of organisms and tissue groups as well as the proteome

SUBMITTER: Huang Q 

PROVIDER: S-EPMC10551891 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature