Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study.

ABSTRACT:

Background

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social and communication skills, restricted interests, and repetitive behaviors. The prevalence of ASD among children in Qatar was recently estimated to be 1.1%, though the genetic architecture underlying ASD both in Qatar and the greater Middle East has been largely unexplored. Here, we describe the first genomic data release from the BARAKA-Qatar Study-a nationwide program building a broadly consented biorepository of individuals with ASD and their families available for sample and data sharing and multi-omics research.

Methods

In this first release, we present a comprehensive analysis of whole-genome sequencing (WGS) data of the first 100 families (372 individuals), inves

SUBMITTER: Abdi M 

PROVIDER: S-EPMC10560429 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature