Dataset Information

Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.

ABSTRACT:

Background/objectives

To date, evidence regarding the protective roles of the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet in patients with type 2 diabetes mellitus (T2DM) is scarce. This study aims to estimate the impact of adhering to the MIND diet on the mortality in patients with and without T2DM.

Subjects/methods

In this cohort study, 6887 participants (1021 patients with T2DM) from the NHANES dataset were analyzed. The exposure is the MIND diet adherence. The primary outcomes are all-cause and cardiovascular (CV) deaths.

Results

We documented 1087 all-cause deaths consisting of 377 CV deaths during the follow-up (median time of 10 years). Among participants with T2DM, those with a high MIND score (> 8.0, range of MIND score: 4.5-13) had a significantly lower risk of all-cause death (hazard ratio [HR] 0.75, 95% confidence interval [CI]: 0.59, 0.96, P = 0.021) and CV death (HR 0.50, 95% CI: 0.29, 0.87, P = 0.014) compared to those with a low MIND score (≤ 8.0). In participants without T2DM, a high MIND score was associated with a significant decrease in the risk of all-cause death (HR = 0.83, 95% CI: 0.70, 0.99, P < 0.001), but the association with CV death risk was not statistically significant.

Conclusion

This study uncovered significant associations between the MIND diet and decreased risk of all-cause and CV death in patients with T2DM. The findings highlight the potential benefits of following the MIND diet in managing and enhancing the outcomes of individuals with T2DM.

SUBMITTER: Song Y

PROVIDER: S-EPMC10564876 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.

Song Yanjun Y Chang Zhen'ge Z Song Chenxi C Cui Kongyong K Shi Boqun B Zhang Rui R Dong Qiuting Q Dou Kefei K

Nutrition & diabetes 20231010 1

<h4>Background/objectives</h4>To date, evidence regarding the protective roles of the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet in patients with type 2 diabetes mellitus (T2DM) is scarce. This study aims to estimate the impact of adhering to the MIND diet on the mortality in patients with and without T2DM.<h4>Subjects/methods</h4>In this cohort study, 6887 participants (1021 patients with T2DM) from the NHANES dataset were analyzed ...[more]

PMID: 37816701

Similar Datasets

Project description:BACKGROUND:Recently, a new eating pattern called as "Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)" has been coined. Emerging studies are examining this dietary pattern with chronic conditions. We aimed to investigate the association between the MIND diet score and general and central obesity among adults. METHODS:This cross-sectional study was conducted in a framework of the Study on the Epidemiology of Psychological Alimentary Health and Nutrition (SEPAHAN). Dietary information was collected using a validated self-administered 106-item Willett-format dish-based semi-quantitative food frequency questionnaire (DS-FFQ) in 6724 adults. Adherence to the MIND diet was examined based on components suggested in this eating pattern. Anthropometrics data were collected using a validated self-reported questionnaire. General obesity was defined as body mass index ?30?kg/m2, and abdominal obesity as waist circumference?>?102?cm for men and?>?88?cm for women. RESULTS:Mean age, BMI and WC in the study population was 36.8?±?8.08 y, 24.9?±?3.8?kg/m2 and 83.7?±?16.02?cm, respectively. Overall, 9.5% of subjects were generally obese and 24.4 were abdominally obese. Examining the whole study population, we found no significant association between the MIND diet score and odds of general obesity, either before (ORs for comparing T3 vs. T1: 1.03; 95% CI: 0.83, 1.27; P-trend?=?0.74) or after controlling for potential confounders (ORs for T3 vs. T1: 0.91; 95% CI: 0.67, 1.25; P-trend?=?0.58). This was also the case for men and women when analyzed separately. We also failed to find any significant association between the MIND diet score and odds of abdominal obesity after controlling for potential confounders in the whole study population (ORs for T3 vs. T1: 1.00, 95% CI: 0.79, 1.27; P-trend?=?0.87). However, women with the greatest adherence to the MIND diet were 19% less likely to be abdominally obese than those with the lowest adherence in crude model (OR?=?0.81; 95% CIs: 0.67, 0.98; P-trend?=?0.03). This association disappeared after controlling for potential confounders (OR?=?0.87; 95% CIs: 0.66, 1.14; P-trend?=?0.55). CONCLUSION:No significant association was observed between adherence to the MIND diet and odds of general and central obesity.

Dataset Information

Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.

Background/objectives

Subjects/methods

Results

Conclusion

Publications

Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts.

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