SARS-CoV-2 variants of concern in children and adolescents with COVID-19: a systematic review.

ABSTRACT:

Objectives

Infections by SARS-CoV-2 variants of concern (VOCs) might affect children and adolescents differently than earlier viral lineages. We aimed to address five questions about SARS-CoV-2 VOC infections in children and adolescents: (1) symptoms and severity, (2) risk factors for severe disease, (3) the risk of infection, (4) the risk of transmission and (5) long-term consequences following a VOC infection.

Design

Systematic review.

Data sources

The COVID-19 Open Access Project database was searched up to 1 March 2022 and PubMed was searched up to 9 May 2022.

Eligibility criteria

We included observational studies about Alpha, Beta, Gamma, Delta and Omicron VOCs among ≤18-year-olds. We included studies in English, German, French, Greek, Italian, Spanish and

SUBMITTER: Wiedenmann M 

PROVIDER: S-EPMC10565293 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature