Association of smoking with cartilage loss of knee osteoarthritis: data from two longitudinal cohorts.

ABSTRACT:

Background

Previous studies have been inconsistent concerning the association between smoking and risk of osteoarthritis (OA). This study aimed to explore the associations of smoking status and change in cartilage volume of OA in two longitudinal cohorts.

Methods

Subjects from the Osteoarthritis Initiative cohort (OAI, n = 593) and the Tasmanian Older Adult Cohort (TASOAC, n = 394) were included in this study. For both cohorts, participants were classified into three groups based on their smoking status, namely 'never', 'former', and 'current' smokers. The outcome measures were the annual rate of change of tibiofemoral cartilage volume over 2 years in OAI and of tibial cartilage volume over 2.6 years in TASOAC. Potential confounders were balanced using the inverse probabilit

SUBMITTER: Shen Z 

PROVIDER: S-EPMC10571432 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature