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Association between Obstructive Sleep Apnea and Heart Failure in Adults-A Systematic Review.


ABSTRACT:

Background

Heart failure (HF) patients commonly experience obstructive sleep apnea (OSA), which may worsen their condition. We reviewed a diverse range of studies to investigate the prevalence of OSA in HF patients, the effects of positive airway pressure (PAP) treatment, and the potential impact of sodium-glucose cotransporter-2 inhibitors (SGLT2i) and sacubitril/valsartan on OSA outcomes.

Methods

We analyzed case-control, observational studies, and randomized controlled trials. Prevalence rates, PAP treatment, and HF pharmacotherapy were assessed.

Results

Numerous studies revealed a high prevalence of OSA in HF patients, particularly with preserved ejection fraction. PAP treatment consistently improved an apnea-hypopnea index, left ventricular ejection fraction, oxy

SUBMITTER: Polecka A 

PROVIDER: S-EPMC10573908 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature