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Synthesis of a Fe₃-Carbyne Motif by Oxidation of an Alkyl Ligated Iron-Sulfur (WFe₃S₃) Cluster.

ABSTRACT: The presence of a carbide ligand in the active site of nitrogenases remains an unusual example of organometallic chemistry employed by a protein. Carbide incorporation into the MFe₇S₉C cluster involves complex biosynthesis, but analogous synthetic methodologies are limited. Herein, we present a new synthetic strategy for incorporating carbon based bridging ligands into iron-sulfur clusters. Starting from a halide precursor, a WFe₃S₃ cluster displaying three terminal alkyl ligands and an open Fe₃ face was prepared. Oxidation results in loss of alkane and formation of a μ₃-carbyne. Characterization of these clusters and mechanistic studies are presented.

SUBMITTER: Scott AG

PROVIDER: S-EPMC10575540 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Synthesis of a Fe3-Carbyne Motif by Oxidation of an Alkyl Ligated Iron-Sulfur (WFe3S3) Cluster.

Scott Anna G AG Agapie Theodor T

Journal of the American Chemical Society 20221220 1

The presence of a carbide ligand in the active site of nitrogenases remains an unusual example of organometallic chemistry employed by a protein. Carbide incorporation into the MFe7S9C cluster involves complex biosynthesis, but analogous synthetic methodologies are limited. Herein, we present a new synthetic strategy for incorporating carbon based bridging ligands into iron-sulfur clusters. Starting from a halide precursor, a WFe3S3 cluster displaying ...[more]

PMID: 36537723

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