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Tricuspid Regurgitation: Disease State and Advances in Percutaneous Therapy.

ABSTRACT: Tricuspid regurgitation (TR) is a relatively common finding. There has been growing recognition of the morbidity and adverse prognosis of severe TR, which affects 1.6 million people in the US. However, symptomatic TR remains undertreated despite emerging therapeutic modalities. In this review, the pathophysiological and epidemiological features of TR are examined and the diagnosis, natural history, and clinical presentation are discussed. An overview of TR therapy is provided, including medical and surgical treatments, as well as novel percutaneous approaches. The currently available studies on percutaneous therapy demonstrate promise for transcatheter valve repair and replacement with favourable clinical outcomes and short-term durability. However, further study is needed.

SUBMITTER: Zhu QM

PROVIDER: S-EPMC10583156 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Tricuspid Regurgitation: Disease State and Advances in Percutaneous Therapy.

Zhu Qiuyu Martin QM Berry Natalia N

European cardiology 20230928

Tricuspid regurgitation (TR) is a relatively common finding. There has been growing recognition of the morbidity and adverse prognosis of severe TR, which affects 1.6 million people in the US. However, symptomatic TR remains undertreated despite emerging therapeutic modalities. In this review, the pathophysiological and epidemiological features of TR are examined and the diagnosis, natural history, and clinical presentation are discussed. An overview of TR therapy is provided, including medical ...[more]

PMID: 37860699

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