A case report of neurosyphilis coexisting with a positive MOG antibody manifested as optic neuritis.

ABSTRACT:

Background

Neurosyphilis refers to an infection of the central nervous system by Treponema pallidum. The clinical manifestations of neurosyphilis are diverse, making it easy to miss or misdiagnose. Anti-myelin oligodendrocyte glycoprotein antibody-associated disease is a recently defined immune-mediated inflammatory demyelinating central nervous system disease. Few studies have reported the coexistence of the two diseases.

Case presentation

This case report presents a 37 years-old male patient with neurosyphilis manifested as optic neuritis with a positive myelin oligodendrocyte glycoprotein (MOG) antibody. This patient received intravenous administration of 3.2 million units of procaine penicillin every 4 h for 2 weeks, followed by a two-week intramuscular injection

SUBMITTER: Shi M 

PROVIDER: S-EPMC10583717 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature