A new procedure for elimination of atrial fibrillation associated with mitral valve disease: a proof-of-concept study.

ABSTRACT:

Background

Left atrial enlargement and fibrosis have been linked to the pathogenesis of atrial fibrillation (AF). The authors aimed to introduce a novel concept and develop a new procedure for AF treatment based on these characteristics.

Methods

The study included three stages. The first stage was a descriptive study to clarify the characteristics of the left atrial enlargement and fibrosis' distribution in patients with mitral valve disease and long-standing persistent AF. Based on these characteristics, the authors introduced a novel concept for AF treatment, and then translated it into a new procedure. The second stage was a proof-of-concept study with this new procedure. The third stage was a comparative effectiveness research to compare the clinical outcomes between pat

SUBMITTER: Chen L 

PROVIDER: S-EPMC10583919 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature