Iodine-Induced Hyperthyroidism and Long-term Risks of Incident Atrial Fibrillation and Flutter.

ABSTRACT:

Context

Although iodine-induced hyperthyroidism is a potential consequence of iodinated radiologic contrast administration, its association with long-term cardiovascular outcomes has not been previously studied.

Objective

To investigate the relationships between hyperthyroidism observed after iodine contrast administration and incident atrial fibrillation/flutter.

Methods

Retrospective cohort study of the U.S. Veterans Health Administration (1998-2021) of patients age ≥18 years with a normal baseline serum thyrotropin (TSH) concentration, subsequent TSH <1 year, and receipt of iodine contrast <60 days before the subsequent TSH. Cox proportional hazards regression was employed to ascertain the adjusted hazard ratio (HR) with 95% CI of incident atrial fibrillation/flutt

SUBMITTER: Inoue K 

PROVIDER: S-EPMC10584637 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature