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Analysis of the relationship between sleep-related disorder and systemic immune-inflammation index in the US population.


ABSTRACT:

Background

The association between sleep-related disorders and inflammation has been demonstrated in previous studies. The systemic immune-inflammation index (SII) is a novel inflammatory index based on leukocytes, but its relationship with sleep-related disorder is unclear. We aimed to investigate the relationship between sleep-related disorder and SII in a nationally representative nonhospitalized sample.

Methods

Data were obtained from the 2005-2008 National Health and Nutrition Examination Survey (NHANES). Exposure variables included self-reported sleep-related disorders, such as sleep duration, sleep problems, high risk of OSA, and daytime sleepiness. SII and other traditional markers of inflammation were considered as outcome variables, including platelet-to-lymphocyte

SUBMITTER: Kadier K 

PROVIDER: S-EPMC10594811 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature