Uneven Expression of 20 Human Papillomavirus Genes Associated with Oropharyngeal Carcinoma.

ABSTRACT:

Background

Human papillomavirus (HPV) is considered to be responsible for 95% of virus-related cancers in many organs. Oropharyngeal carcinoma (OC) is distinguished by the transformation of the healthy epithelium into precancerous cells.

Aim

The current study sought to examine the uneven gene expression of 20 genes among those scanned by microarray for oropharyngeal cancer patients.

Materials and methods

The GSE56142 dataset was extracted from the Gene Expression Omnibus of the National Center for Biotechnology Information; 24 specimens were evaluated. Gene ontology (GO), the Kyoto Encyclopedia of Genes and Genomes, and the protein-protein interaction (PPI) were used to depict the biological roles of the genes under investigation using types of software.

Results

SUBMITTER: Dawood AA 

PROVIDER: S-EPMC10619986 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature