Dataset Information

The association between symptoms of gastroesophageal reflux disease and perceived stress: A countrywide study of Sri Lanka.

ABSTRACT:

Background/aims

Stress is a known associated factor for gastroesophageal reflux disease (GERD). However, the dynamics between stress and GERD are not fully studied, especially in Sri Lanka. Our objective was to assess it.

Methods

For this cross-sectional descriptive study, 1200 individuals (age ranged 18-70 years, mean 42.7 years [SD 14.4 years], 46.1% males), were recruited using stratified random cluster sampling from all 25 districts of Sri Lanka. An interviewer-administered questionnaire, which included a country-validated GERD symptom screening tool, and the Perceived Stress Scale (PSS), was used to assess GERD symptoms and stress. Probable GERD was defined as those having heartburn and/ or regurgitation at least once per week which is on par with globally accepted criteria. Those who did not fulfill these criteria were considered as controls.

Results

PSS score was higher in those with probable GERD (mean 13.75 [standard deviation (SD) 6.87]) than in controls (mean 10.93 [SD 6.80]), (p <0.001, Mann-Whitney U test). The adjusted odds ratio for GERD symptoms was 1.96 times higher (95% confidence interval 1.50-2.55) in the moderate to high-stress level compared to the low-stress level participants. PSS score correlated significantly with the GERD screening tool score (R 0.242, p <0.001). Heartburn, regurgitation, chest pain, cough, and burping were significantly frequent in those with moderate to high-stress levels (p <0.001). Those with higher stress scores were more likely to use acid-lowering drugs (p = 0.006).

Conclusions

Individuals exposed to higher levels of stress are more likely to have GERD symptoms. Therefore, stress reduction should be an important part of GERD symptom management.

SUBMITTER: Wickramasinghe N

PROVIDER: S-EPMC10635461 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Publications

The association between symptoms of gastroesophageal reflux disease and perceived stress: A countrywide study of Sri Lanka.

Wickramasinghe Nilanka N Thuraisingham Ahthavann A Jayalath Achini A Wickramasinghe Dakshitha D Samarasekara Nandadeva N Yazaki Etsuro E Devanarayana Niranga Manjuri NM

PloS one 20231109 11

<h4>Background/aims</h4>Stress is a known associated factor for gastroesophageal reflux disease (GERD). However, the dynamics between stress and GERD are not fully studied, especially in Sri Lanka. Our objective was to assess it.<h4>Methods</h4>For this cross-sectional descriptive study, 1200 individuals (age ranged 18-70 years, mean 42.7 years [SD 14.4 years], 46.1% males), were recruited using stratified random cluster sampling from all 25 districts of Sri Lanka. An interviewer-administered qu ...[more]

PMID: 37943748

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Dataset Information

The association between symptoms of gastroesophageal reflux disease and perceived stress: A countrywide study of Sri Lanka.

Background/aims

Methods

Results

Conclusions

Publications

The association between symptoms of gastroesophageal reflux disease and perceived stress: A countrywide study of Sri Lanka.

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