Ontology highlight
ABSTRACT:
SUBMITTER: Longfield SF
PROVIDER: S-EPMC10638352 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Longfield Shanley F SF Mollazade Mahdie M Wallis Tristan P TP Gormal Rachel S RS Joensuu Merja M Wark Jesse R JR van Waardenberg Ashley J AJ Small Christopher C Graham Mark E ME Meunier Frédéric A FA Martínez-Mármol Ramón R
Nature communications 20231110 1
Neuronal communication relies on the release of neurotransmitters from various populations of synaptic vesicles. Despite displaying vastly different release probabilities and mobilities, the reserve and recycling pool of vesicles co-exist within a single cluster suggesting that small synaptic biomolecular condensates could regulate their nanoscale distribution. Here, we performed a large-scale activity-dependent phosphoproteome analysis of hippocampal neurons in vitro and identified Tau as a hig ...[more]