Relationship between magnetic resonance imaging findings and histological grade in spinal peripheral nerve sheath tumors in dogs.

ABSTRACT:

Background

Peripheral nerve sheath tumors (PNSTs) are a group of neoplasms originating from Schwann cells or pluripotent cell of the neural crest. Therapeutic options and prognosis are influenced by their degree of malignancy and location.

Hypothesis/objectives

Identify magnetic resonance imaging (MRI) features predictive of PNST histologic grade.

Animals

Forty-four dogs with histopathological diagnosis of spinal PNSTs and previous MRI investigation.

Methods

A multicenter retrospective study including cases with (a) histopathologic diagnosis of PNST and (b) MRI studies available for review. Histologic slides were reviewed and graded by a board-certified pathologist according to a modified French system (FNCLCC) for grading soft tissue sarcomas. The MRI studies

SUBMITTER: Morabito S 

PROVIDER: S-EPMC10658554 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature