Diet order affects energy balance in randomized crossover feeding studies that vary in macronutrients but not ultra-processing.

ABSTRACT:

Background

Crossover studies can induce order effects, especially when they lack a wash-out period.

Objective

To explore diet order effects on energy balance and food intake between randomized diet order groups in two inpatient crossover studies originally designed to compare within-subject differences in ad libitum energy intake between either minimally processed low carbohydrate (LC) versus low fat (LF) diets or macronutrient-matched diets composed of mostly minimally processed food (MPF) or ultra-processed food (UPF).

Methods

Diet order group comparisons of changes in body weight, body composition, and differences in energy expenditure, and food intake were assessed over four weeks in 20 adults randomized to either the LC followed immediately by the LF diet

SUBMITTER: Sciarrillo CM 

PROVIDER: S-EPMC10659501 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature