Histopathological and biomarker complete response after neoadjuvant chemotherapy of advanced stage yolk sac tumor of the ovary: A case report and literature review.

ABSTRACT:

Introduction

Yolk sac tumor is the second most common germ cell ovarian carcinoma. Neoadjuvant chemotherapy (NACT) is proposed as an alternative option for patients with advanced disease who are not eligible for primary debulking. We presented a case with a systematic review of advanced yolk sac tumors of the ovary with poor performance who gain benefit from NACT.

Case presentation

A 24-year-old female underwent NACT followed by surgery after being diagnosed with an advanced yolk sac tumor. A literature search was done based on the clinical question using the Patient/Problem, Intervention, Comparison, and Outcome (PICO) approach. Pubmed and Google Scholar were used to search the literature.

Discussion

Out of 111 manuscripts found, 2 articles were retrieved for detaile

SUBMITTER: Utami TW 

PROVIDER: S-EPMC10667731 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature