Improving tractography in brainstem cavernoma patients by distortion correction.

ABSTRACT:

Introduction

The resection of brainstem cerebral cavernous malformations (CCM) harbors the risk of damaging the corticospinal tract (CST) and other major tracts. Hence, visualization of eloquent fiber tracts supports pre- and intraoperative planning. However, diffusion tensor imaging fiber tracking at brainstem level suffers from distortion due to field inhomogeneities and eddy currents by steep diffusion gradients.

Research question

This study aims to analyze the effect of distortion correction for CST tractography in brainstem CCM patients.

Material and methods

25 patients who underwent resection of brainstem CCM were enrolled, 24 suffered from hemorrhage. We performed an anatomically based tractography of the CST with a mean minimal fractional anisotropy of 0.22 ± 

SUBMITTER: Liang R 

PROVIDER: S-EPMC10668098 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature