Methods for Developing a Process Design Space Using Retrospective Data.
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ABSTRACT:
SUBMITTER: Romero-Obon M
PROVIDER: S-EPMC10675834 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
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Methods for Developing a Process Design Space Using Retrospective Data.
Romero-Obon Miquel M Pérez-Lozano Pilar P Rouaz-El-Hajoui Khadija K Suñé-Pou Marc M Nardi-Ricart Anna A Suñé-Negre Josep M JM García-Montoya Encarna E
Pharmaceutics 20231116 11
Prospectively planned designs of experiments (DoEs) offer a valuable approach to preventing collinearity issues that can result in statistical confusion, leading to misinterpretation and reducing the predictability of statistical models. However, it is also possible to develop models using historical data, provided that certain guidelines are followed to enhance and ensure proper statistical modeling. This article presents a methodology for constructing a design space using process data, while a ...[more]
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