The association of increased body mass index on cardiorespiratory fitness, physical activity, and cognition in adults with down syndrome.

ABSTRACT:

Background

Obesity is a significant risk factor for Alzheimer's disease; however, this association has not been explored in adults with Down syndrome.

Objective

To examine the association of obesity, assessed by body mass index (BMI), with factors related to Alzheimer's disease risk including cardiorespiratory fitness, physical activity, and cognition in adults with Down syndrome.

Methods

Adults with Down syndrome attended a laboratory visit where BMI, cardiorespiratory fitness (VO_{2 peak}), and cognitive function (CANTAB® DS Battery) were obtained. Physical activity (accelerometer) was collected over the week following the laboratory visit. Wilcoxon rank sum tests were used to evaluate differences in cardiorespiratory fitness, sedentary time, moderate-to-vig

SUBMITTER: Dodd D 

PROVIDER: S-EPMC10680094 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature