A meta-analysis of rice phosphoproteomics data to understand variation in cell signalling across the rice pan-genome.

ABSTRACT: Phosphorylation is the most studied post-translational modification, and has multiple biological functions. In this study, we have re-analysed publicly available mass spectrometry proteomics datasets enriched for phosphopeptides from Asian rice (Oryza sativa). In total we identified 15,522 phosphosites on serine, threonine and tyrosine residues on rice proteins. We identified sequence motifs for phosphosites, and link motifs to enrichment of different biological processes, indicating different downstream regulation likely caused by different kinase groups. We cross-referenced phosphosites against the rice 3,000 genomes, to identify single amino acid variations (SAAVs) within or proximal to phosphosites that could cause loss of a site in a given rice variety. The data was clustered t

SUBMITTER: Ramsbottom KA 

PROVIDER: S-EPMC10680829 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature