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Distribution, inducibility, and characteristics of Latilactobacillus curvatus temperate phages.


ABSTRACT: Aim: Temperate phages are known to heavily impact the growth of their host, be it in a positive way, e.g., when beneficial genes are provided by the phage, or negatively when lysis occurs after prophage induction. This study provides an in-depth look into the distribution and variety of prophages in Latilactobacillus curvatus (L. curvatus). This species is found in a wide variety of ecological niches and is routinely used as a meat starter culture. Methods: Fourty five L. curvatus genomes were screened for prophages. The intact predicted prophages and their chromosomal integration loci were described. Six L. curvatus lysogens were analysed for phage-mediated lysis post induction via UV light and/or mitomycin C. Their lysates were analysed for phage

SUBMITTER: Ambros CL 

PROVIDER: S-EPMC10688831 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature