Structural and functional connectivity alteration patterns of the cingulate gyrus in Type 2 diabetes.

ABSTRACT:

Objective

We aimed to reveal the role of structural and functional alterations of cingulate gyrus in early cognitive impairment in Type 2 diabetes mellitus (T2DM) patients.

Methods

Fifty-six T2DM patients and 60 healthy controls (HCs) underwent a neuropsychological assessment and sagittal three-dimensional T1-weighted and resting-state functional MRI. Differences in the cortical thickness of the cingulate cortex and the functional connectivity (FC) of the nine subregions of the cingulate gyrus and the whole brain were compared between T2DM patients and HCs. Correlation analysis was performed between cortex thickness and FC and the participants' clinical/cognitive variables.

Results

The cortical thickness of the cingulate gyrus was not significantly different between T

SUBMITTER: Zhang D 

PROVIDER: S-EPMC10723245 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature