Microfluidic devices for precise measurements of cell directionality reveal a role for glutamine during cell migration.
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ABSTRACT:
SUBMITTER: Gural N
PROVIDER: S-EPMC10754855 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Publications
Microfluidic devices for precise measurements of cell directionality reveal a role for glutamine during cell migration.
Scientific reports 20231227 1
Cancer cells that migrate from tumors into surrounding tissues are responsible for cancer dissemination through the body. Microfluidic devices have been instrumental in discovering unexpected features of cancer cell migration, including the migration in self-generated gradients and the contributions of cell-cell contact during collective migration. Here, we design microfluidic channels with five successive bifurcations to characterize the directionality of cancer cell migration with high precisi ...[more]
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