Borane-Pyridine: An Efficient Catalyst for Direct Amidation.

ABSTRACT: Borane-pyridine acts as an efficient (5 mol%) liquid catalyst, providing improved solubility for the direct amidation of a wide range of aromatic and aliphatic carboxylic acids and amines to form secondary and tertiary carboxamides. Tolerance of potentially incompatible halo, nitro, and alkene functionalities has been demonstrated.

SUBMITTER: Ramachandran PV 

PROVIDER: S-EPMC10780903 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature