Coronary flow capacity and survival prediction after revascularization: physiological basis and clinical implications.

ABSTRACT:

Background and aims

Coronary flow capacity (CFC) is associated with an observed 10-year survival probability for individual patients before and after actual revascularization for comparison to virtual hypothetical ideal complete revascularization.

Methods

Stress myocardial perfusion (mL/min/g) and coronary flow reserve (CFR) per pixel were quantified in 6979 coronary artery disease (CAD) subjects using Rb-82 positron emission tomography (PET) for CFC maps of artery-specific size-severity abnormalities expressed as percent left ventricle with prospective follow-up to define survival probability per-decade as fraction of 1.0.

Results

Severely reduced CFC in 6979 subjects predicted low survival probability that improved by 42% after revascularization compared with no rev

SUBMITTER: Gould KL 

PROVIDER: S-EPMC10787661 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature