Preoperative identification of small parathyroid adenomas-better done by fluorocholine positron emission tomography/computed tomography.

ABSTRACT:

Background

Preoperative localization imaging studies are crucial for safe and successful parathyroidectomy in patients with primary hyperparathyroidism (pHPT), especially in focused approaches. A common imaging sequence is ultrasound followed by scintigraphy. These techniques, but not 18F-fluorocholine positron emission tomography/computed tomography (PET/CT), show lower detection rates in multiglandular disease (MGD), which is associated with smaller adenomas. In this study, we evaluate the accuracy of these modalities in small parathyroid adenomas (PAs) and discuss the potential sequence of preoperative localization diagnostics.

Methods

Patients undergoing parathyroidectomy for pHPT were retrospectively categorized into small adenoma (specimen diameter <10 mm) and large ad

SUBMITTER: Wolf HW 

PROVIDER: S-EPMC10788562 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature