The role of ¹⁸F-fluoromethylcholine-positron emission tomography-computed tomography for preoperative localization of hyperfunctioning parathyroid glands with special emphasis on multiglandular disease: a retrospective cohort study.

ABSTRACT:

Background

Primary hyperparathyroidism (PHPT) is a common endocrine disorder. Definitive treatment is surgical. Preoperative localization of diseased glands increases the chance of successful treatment. The aim of this study is to investigate the diagnostic performance of ¹⁸F-fluoromethylcholine-positron emission tomography-computed tomography (¹⁸F-FCh-PET-CT) in preoperative localization of diseased parathyroid glands, when first-line examinations were inconclusive.

Methods

This is a retrospective study. All patients with PHPT who underwent ¹⁸F-FCh-PET-CT, after inconclusive ultrasound examination and ^99mTc-methoxyisobutylisonitrile/single-photon emission CT-CT, were included in cohort I. Patients who were subsequently operated fo

SUBMITTER: Murad H 

PROVIDER: S-EPMC10721563 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature