Type IV pilus retraction is required for Neisseria musculi colonization and persistence in a natural mouse model of infection.

ABSTRACT:

Importance

We describe the importance of Type IV pilus retraction to colonization and persistence by a mouse commensal Neisseria, N. musculi, in its native host. Our findings have implications for the role of Tfp retraction in mediating interactions of human-adapted pathogenic and commensal Neisseria with their human host due to the relatedness of these species.

SUBMITTER: Rhodes KA 

PROVIDER: S-EPMC10790696 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature