Treatment modalities favoring outcome in well-differentiated neuroendocrine tumors G3.

ABSTRACT:

Introduction

Neuroendocrine neoplasms (NEN) are a rare and heterogenous group of tumors arising from neuroendocrine cells in multiple organs. Neuroendocrine tumors (NET) G3 encompass a small subgroup accounting for less than 10% of all neuroendocrine neoplasms. In contrast to NET G1 and G2 as well as neuroendocrine carcinomas (NEC), in NET G3 data on treatment and patient outcomes are still limited. Especially in a metastasized tumor stage, the role of surgery, peptide receptor radionucleotide therapy (PRRT), and systemic chemotherapy is not clearly defined.

Methods

In this real-life cohort, we consecutively analyzed clinical outcome in NET G3 patients receiving different diagnostic and treatment.

Results and discussion

We found that even metastasized NET G3 patients

SUBMITTER: Hinterleitner M 

PROVIDER: S-EPMC10800837 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature