Competing Genetic Traits and Their Influence on LDL Cholesterol Concentration in Familial Hypercholesterolemia.

ABSTRACT: Familial hypercholesterolemia is a monogenic disorder that leads to premature atherosclerosis as a result of lifelong exposure to elevated low-density lipoprotein cholesterol (LDL-C). Both genetic traits and lifestyle factors can influence LDL-C levels. Adults with LDL-C of 170 mg/dL and higher may benefit from genetic evaluation to accurately assess their risk of atherosclerosis.

SUBMITTER: Song C 

PROVIDER: S-EPMC10801839 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature