Impact of vertical positioning on lung aeration among mechanically ventilated intensive care unit patients: a randomized crossover clinical trial.

ABSTRACT:

Objective

To assess the impact of different vertical positions on lung aeration in patients receiving invasive mechanical ventilation.

Methods

An open-label randomized crossover clinical trial was conducted between January and July 2020. Adults receiving invasive mechanical ventilation for > 24 hours and < 7 days with hemodynamic, respiratory and neurological stability were randomly assigned at a 1:1 ratio to the sitting position followed by passive orthostasis condition or the passive orthostasis followed by the sitting position condition. The primary outcome was lung aeration assessed using the lung ultrasound score (score ranges from 0 [better] to 36 [worse]).

Results

A total of 186 subjects were screened; of these subjects, 19 were enrolled (57.8% male; mean age,

SUBMITTER: Neves D 

PROVIDER: S-EPMC10802776 | biostudies-literature | 2023 Oct-Dec

REPOSITORIES: biostudies-literature