Two way workable microchanneled hydrogel suture to diagnose, treat and monitor the infarcted heart.
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ABSTRACT:
SUBMITTER: Xue F
PROVIDER: S-EPMC10824767 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
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Two way workable microchanneled hydrogel suture to diagnose, treat and monitor the infarcted heart.
Xue Fangchao F Zhao Shanlan S Tian Hao H Qin Haoxiang H Li Xiaochen X Jian Zhao Z Du Jiahui J Li Yanzhao Y Wang Yanhong Y Lin Lin L Liu Chen C Shang Yongning Y He Lang L Xing Malcolm M Zeng Wen W
Nature communications 20240129 1
During myocardial infarction, microcirculation disturbance in the ischemic area can cause necrosis and formation of fibrotic tissue, potentially leading to malignant arrhythmia and myocardial remodeling. Here, we report a microchanneled hydrogel suture for two-way signal communication, pumping drugs on demand, and cardiac repair. After myocardial infarction, our hydrogel suture monitors abnormal electrocardiogram through the mobile device and triggers nitric oxide on demand via the hydrogel sutu ...[more]
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