Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals.

ABSTRACT:

Objectives

Bloodstream infections (BSIs) acquired in the ICU represent a detrimental yet potentially preventable condition. We determined the prevalence of BSI acquired in the ICU (ICU-onset BSI), pathogen profile, and associated risk factors.

Design

Retrospective cohort study.

Data sources

Eighty-five U.S. hospitals in the Cerner Healthfacts Database.

Patient selection

Adult hospitalizations between January 2009 and December 2015 including a (≥ 3 d) ICU stay.

Data extraction and data synthesis

Prevalence of ICU-onset BSI (between ICU Day 3 and ICU discharge) and associated pathogen and antibiotic resistance distributions were compared with BSI present on (ICU) admission (ICU-BSI POA ); and BSI present on ICU admission day or Day 2. Cox models identified

SUBMITTER: Gouel-Cheron A 

PROVIDER: S-EPMC10829879 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature