Prevalence of frailty and association with patient centered outcomes: A prospective registry-embedded cohort study from India.

ABSTRACT:

Purpose

We aimed to study the prevalence of frailty, evaluate risk factors, and understand impact on outcomes in India.

Methods

This was a prospective registry-embedded cohort study across 7 intensive care units (ICUs) and included adult patients anticipated to stay for at least 48 h. Primary exposure was frailty, as defined by a score ≥ 5 on the Clinical Frailty Scale and primary outcome was ICU mortality. Secondary outcomes included in-hospital mortality and resource utilization. We used generalized linear models to evaluate risk factors and model association between frailty and outcomes.

Results

838 patients were included, with median (IQR) age 57 (42,68) yrs.; 64.8% were male. Prevalence of frailty was 19.8%. Charlson comorbidity index (OR:1.73 (95%CI:1.39,2.15)),

SUBMITTER: Tirupakuzhi Vijayaraghavan BK 

PROVIDER: S-EPMC10830405 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature