The impact of fluorine-18-fluoroethyltyrosine positron emission tomography scan timing on radiotherapy planning in newly diagnosed patients with glioblastoma.

ABSTRACT:

Background and purpose

Glioblastoma is one of the most common and aggressive primary brain tumours in adults. Though radiation therapy (RT) techniques have progressed significantly in recent decades, patient survival has seen little improvement. However, an area of promise is the use of fluorine-18-fluoroethyltyrosine positron-emission-tomography (¹⁸F-FET PET) imaging to assist in RT target delineation. This retrospective study aims to assess the impact of ¹⁸F-FET PET scan timing on the resultant RT target volumes and subsequent RT plans in post-operative glioblastoma patients.

Materials and methods

The imaging and RT treatment data of eight patients diagnosed with glioblastoma and treated at a single institution were analysed. Before starting RT, each

SUBMITTER: Ryan J 

PROVIDER: S-EPMC10831153 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature