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ABSTRACT: Background
With continuously aging societies, an increase in the number of people with cognitive decline is to be expected. Aside from the development of causative treatments, the successful implementation of prevention strategies is of utmost importance to reduce the high societal burden caused by neurodegenerative diseases leading to dementia among which the most common cause is Alzheimer's disease.Objective
The aim of the Luxembourgish "programme dementia prevention (pdp)" is to prevent or at least delay dementia in an at-risk population through personalized multi-domain lifestyle interventions. The current work aims to provide a detailed overview of the methodology and presents initial results regarding the cohort characteristics and the implementation process.Methods
In the frame of the pdp, an extensive neuropsychological evaluation and risk factor assessment are conducted for each participant. Based on the results, individualized multi-domain lifestyle interventions are suggested.Results
A total number of 450 participants (Mean age = 69.5 years; SD = 10.8) have been screened at different recruitment sites throughout the country, among whom 425 participants (94.4%) met the selection criteria.Conclusions
We provide evidence supporting the feasibility of implementing a nationwide dementia prevention program and achieving successful recruitment of the target population by establishing a network of different healthcare providers.
SUBMITTER: Schroder VE
PROVIDER: S-EPMC10836551 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
Schröder Valerie E VE Skrozic Amna A Erz Dorothee D Kaysen Anne A Fritz Joëlle V JV Loureiro Joao M JM McIntyre Deborah D Pauly Laure L Kemp Jennifer J Schmitz Sabine K SK Wagner Sophie S Reyes Margarita M Soare Ruxandra R Satagopam Venkata V Vega Carlos C Gawron Piotr P Roomp Kirsten K Conde Patricia Martins PM Klucken Jochen J Köhler Sebastian S Hartmann Tobias T Dodel Richard R Leist Anja K AK Kalbe Elke E Krüger Rejko R
Journal of Alzheimer's disease : JAD 20240101 2
<h4>Background</h4>With continuously aging societies, an increase in the number of people with cognitive decline is to be expected. Aside from the development of causative treatments, the successful implementation of prevention strategies is of utmost importance to reduce the high societal burden caused by neurodegenerative diseases leading to dementia among which the most common cause is Alzheimer's disease.<h4>Objective</h4>The aim of the Luxembourgish "programme dementia prevention (pdp)" is ...[more]