Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.

ABSTRACT:

Introduction

The Rey Auditory Verbal Learning Test (RAVLT) is a useful neuropsychological test for describing episodic memory impairment in dementia. However, there is limited research on its utility in early-onset Alzheimer's disease (EOAD). We assess the influence of amyloid and diagnostic syndrome on several memory scores in EOAD.

Methods

We transcribed RAVLT recordings from 303 subjects in the Longitudinal Early-Onset Alzheimer's Disease Study. Subjects were grouped by amyloid status and syndrome. Primacy, recency, J-curve, duration, stopping time, and speed score were calculated and entered into linear mixed effects models as dependent variables.

Results

Compared with amyloid negative subjects, positive subjects exhibited effects on raw score, primacy, recency, a

SUBMITTER: Bushnell J 

PROVIDER: S-EPMC10855009 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature