Steatotic Liver Disease and Sepsis Outcomes-A Prospective Cohort Study (SepsisFAT).

ABSTRACT: Background: While it has been shown that steatotic liver disease (SLD) is associated with systemic changes in immune response, the impact of SLD on sepsis outcomes has not yet been established. The aim of this study was to investigate the association between SLD and sepsis severity and outcomes. Methods: A prospective observational study included consecutively hospitalized adult patients with community-acquired sepsis during a 16-month period. Results: Of the 378 included patients (49.5% male, median age of 69, IQR 57-78 years), 174 (46%) were diagnosed with SLD. Patients with SLD were older and more frequently fulfilled the criteria for metabolic syndrome. There were no differences in the source and etiology of sepsis between the groups. Patients with SLD exhibited a

SUBMITTER: Krznaric J 

PROVIDER: S-EPMC10856507 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature