SQLE is a promising prognostic and immunological biomarker and correlated with immune Infiltration in Sarcoma.
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ABSTRACT:
SUBMITTER: Shao M
PROVIDER: S-EPMC10861000 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
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SQLE is a promising prognostic and immunological biomarker and correlated with immune Infiltration in Sarcoma.
Shao Mengwei M Wang Mingbo M Wang Xiliang X Feng Xiaodong X Zhang Lifeng L Lv Huicheng H
Medicine 20240201 6
Squalene epoxidase (SQLE) is an essential enzyme involved in cholesterol biosynthesis. However, its role in sarcoma and its correlation with immune infiltration remains unclear. All original data were downloaded from The Cancer Genome Atlas (TCGA). SQLE expression was explored using the TCGA database, and correlations between SQLE and cancer immune characteristics were analyzed via the TISIDB databases. Generally, SQLE is predominantly overexpressed and has diagnostic and prognostic value in sar ...[more]
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