Romer-EPTI: rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale dMRI and microstructure imaging.

ABSTRACT:

Purpose

To overcome the major challenges in dMRI acquisition, including low SNR, distortion/blurring, and motion vulnerability.

Methods

A novel Romer-EPTI technique is developed to provide distortion-free dMRI with significant SNR gain, high motion-robustness, sharp spatial resolution, and simultaneous multi-TE imaging. It introduces a ROtating-view Motion-robust supEr-Resolution technique (Romer) combined with a distortion/blurring-free EPTI encoding. Romer enhances SNR by a simultaneous multi-thick-slice acquisition with rotating-view encoding, while providing high motion-robustness through a motion-aware super-resolution reconstruction, which also incorporates slice-profile and real-value diffusion, to resolve high-isotropic-resolution volumes. The in-plane encoding is pe

SUBMITTER: Dong Z 

PROVIDER: S-EPMC10862730 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature